Infrastructure systems lose functionality continuously because of increasing demands imposed by extreme natural events and socioeconomic pressures. According to the World Risk Report 2016, inadequate infrastructure raises the frequency of losses to life and property, and the risk that extreme natural events might become disasters. The ASCE estimates that the United States alone faces a US$2.59 trillion shortfall in infrastructure needs in the next ten years. In addition, according to the OCED, the Global infrastructure investment needs in adaptation will be about $6.3 Trillion annually until 2050. In the context of rapidly increasing demands and limited resources, it is necessary to rethink how infrastructure is planned and executed. This task requires a new understanding of infrastructure as dynamic systems that i) are modeled as a process; ii) evolve continuously; iii) can change and adjust to new circumstances as they materialize; and iv) are interconnected with other systems and the social, economic, and environmental surroundings. This seminar presents the importance and benefits of looking at existing and new infrastructure as dynamic systems, with flexible features, that facilitate the efficient response to new and unplanned events as they unravel throughout their lifetime.